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目的：了解磁共振成像在前列腺癌和良性前列腺增生诊断与鉴别诊断的价值。方法：本文对２１例有手术病理证实的前列腺癌和良性前列腺增生的病人进行ＭＲ检查，并与组织病理作对比研究。其中６例前列腺癌，２例前列腺肉瘤，１３例良性前列腺增生。采用自旋回波（ＳＥ）Ｔ１和Ｔ２加权像对所有病例进行分析。结果：ＭＲＴ２加权像５２％（１１／２１）的病人显示位于前列腺两侧及后部的边缘带腺体呈高信号，而中央带的腺体呈低信号。７６％（１０／１３）的良性前列腺增生显示为中央带腺体增大呈较低信号强度而两侧高信号的边缘带腺体呈压缩变薄的改变。在前列腺癌和肉瘤中７例表现为ＭＲＴ２加权像一侧或两侧的边缘带高信号消失，且周边不见低信号的纤维包膜。２１例前列腺增生与癌的诊断准确率为８０．９％。此外本文还对肿瘤外侵的估计作了初步探讨。结论：我们认为ＭＲ在前列腺增生和癌的诊断和鉴别诊断上有应用价值。
Objective: To understand the value of magnetic resonance imaging in the diagnosis and differential diagnosis of prostate cancer and benign prostatic hyperplasia. Methods: Twenty-one patients with pathologically proven prostate cancer and benign prostatic hyperplasia were examined by MR imaging and compared with histopathology. Among them, 6 cases of prostate cancer, 2 cases of prostate sarcoma, 13 cases of benign prostatic hyperplasia. All cases were analyzed using spin echo (SE) T1 and T2 weighted images. RESULTS: Fifty-two percent (11/21) of patients with MRT2-weighted images showed a high signal in the marginal glands located on both sides of the prostate and posterior, while the glands in the central band showed a low signal. 76% (10/13) of benign prostatic hyperplasia showed a lesser signal intensity in the central gland enlargement and a thinning change in the glandular margin of the high signal on both sides. Seven cases of prostate cancer and sarcoma showed high signal disappeared on one or both sides of the MRT2 weighted image, and no low signal fiber envelope was seen in the periphery. 21 cases of benign prostatic hyperplasia and cancer diagnostic accuracy was 80.9%. In addition, this article also made a preliminary study on the estimation of tumor invasion. Conclusion: We think MR has application value in the diagnosis and differential diagnosis of benign prostatic hyperplasia and cancer.