论文部分内容阅读
酚的同系物許多是防腐杀菌剂(苯酚、苯甲酚),但由于一元酚、二元酚均有相当的毒性如刺激性,且杀菌力很低。因而实用价值較小。目前广泛应用酒精作为皮肤组織的杀菌药,我国的酒精在这方面的消耗量相当大。但在發展合成化学工業的今日,节省和控制酒精在非工業性生产方面的消費量是必要的,加之酒精还不宜在軟部组織(粘膜系統)上使用,而适用于軟部组织的药物(陽性界面活性杀菌剂)尚感缺乏。因此作者认为,利用有防腐杀菌作用的某些化合物,经化学方法处理后,使局部地改变某些構型。以期降低它們的毒性如刺激性,增强其杀菌效能是有現实意义的。作者试用间苯二酚经乙酰化而制得一乙酰間苯二酚(Mononcetylresorcin)或間苯酚乙酯。本文仅將此剂
Many of the phenolic homologs are antiseptic germicides (phenol, cresol), but due to the monophenols, dihydric phenols have considerable toxicity such as irritation and low bactericidal power. Therefore, less practical value. At present, alcohol is widely used as a dermatological bactericide, and the consumption of alcohol in China in this area is quite large. However, in the development of the synthetic chemical industry, it is necessary to save and control the consumption of alcohol in non-industrial production. In addition, the alcohol should not be used in the soft tissue (mucosal system) and the soft tissue (positive Interface active fungicide) is still lacking. Therefore, the author believes that the use of certain anti-bacterial effect of certain compounds, after chemical treatment, to make some changes in the local configuration. In order to reduce their toxicity such as irritation, enhance their bactericidal efficacy is of practical significance. The authors try to resorcinol acetylation of acetylation resorcinol (Mononcetylresorcin) or m-phenylethyl ester. This article only this agent