论文部分内容阅读
目的探讨人血红细胞溶血的辐射剂量效应、时间效应，并进一步研究细菌ＳＯＤ对辐射溶血的防护效应。方法溶血程度用比色法测量。结果随辐射剂量的增大，溶血光密度增大，同一辐射剂量其辐射溶血随时间的延长而加剧；加细菌ＳＯＤ组辐射溶血光密度均比辐射组低，甚至比自然溶血光密度低，而且辐射前加ＳＯＤ组溶血光密度比辐射后加ＳＯＤ组低。结论溶血程度与辐射剂量及时间正相关，在同一辐射剂量下，细菌ＳＯＤ在３０～４００ＩＵ的范围内，酶活力单位越高，辐射防护效果越好，辐射前加ＳＯＤ比辐射后加ＳＯＤ效果好
Objective To investigate the radiation dose effect and time effect of hemolysis of human erythrocytes and further study the protective effect of bacterial SOD on radiation hemolysis. Methods Hemolysis was measured by colorimetry. Results With the increase of radiation dose, the hemolytic optical density increased, and the radiation hemolysis of the same dose of radiation increased with the extension of time. The optical density of radiation hemolysis in bacterial SOD group was lower than that of radiation group, even lower than the natural hemolysis optical density The hemolysis optical density of pre-irradiation plus SOD group was lower than that of superoxide dismutase plus radiation group. Conclusions The degree of hemolysis is positively correlated with the dose and time of radiation. Under the same radiation dose, the bacterial SOD is in the range of 30-400 IU. The higher the unit of enzyme activity is, the better the radiation protection effect is.