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智能药物是由智能高分子载体构成的具有自我反馈功能的给药系统,这种智能性主要表现在智能高分子载体上,而所谓的智能高分子载体材料是指通过系统协调材料内部的各种功能,对环境可感知且可响应,并且具有功能发现能力的一种新材料。智能高分子材料中研究最广泛的为环境响应性高分子凝胶,它能对周围的环境刺激因素,如温度、pH、离子、电场、磁场、溶剂、反应物、光或应力等做出有效响应并且自身性质也随之发生变化,即发生膨胀与收缩,这种膨胀有时能达到几十倍乃至几千倍。由于环境响应高分子凝胶的独特响应性,在化学化工、生物医学、药物载体等方面具有很好的应用前景。
The intelligent drug is a self-feedback drug delivery system composed of intelligent polymer carriers. The intelligence mainly manifests in the smart polymer carrier. The so-called smart polymer carrier material refers to a system that coordinates various kinds of materials Function, environment-aware and responsive, and has a new material for functional discovery. The most widely studied intelligent polymer materials are environmentally-responsive polymer gels that are effective at surrounding environmental stimuli such as temperature, pH, ions, electric fields, magnetic fields, solvents, reactants, light or stress Response and its own nature also will change, that is, expansion and contraction, the expansion can sometimes reach tens of times or even thousands of times. Due to the unique responsiveness of environment-responsive polymer gels, it has good application prospect in chemical engineering, biomedicine and drug carrier.