目的探讨64层螺旋CT冠状动脉造影的临床应用。方法选取我院2015年6月至2016年6月48例疑似冠心病(CHD)患者,所有患者均经64层螺旋CT冠状动脉造影检查与选择性冠状动脉造影检查(CAG),以性冠状动脉造影检查结果为标准,评价64层螺旋CT冠状动脉造影检查的准确性,同时对冠状动脉病变不同部位和狭窄程度的64层螺旋CT冠状动脉造影检查结果进行分析。结果 48例疑似冠心病患者CT冠状动脉成像检查准确性93.6%,敏感性92.8%,特异性87.5%,阳性预测值95.4%和阴性预测值79.8%;冠状动脉近端血管的检查结果好于冠状动脉远端血管的检查结果;冠状动脉狭窄程度越重的血管其检查结果好于冠状动脉狭窄程度轻的血管的检查结果。结论 64层螺旋CT冠状动脉造影是一种无创、简便、经济、安全可靠的筛查冠心病的方法,并可对冠状动脉形态学进行良好的评价,从而进行介入治疗的筛选。 Objective To explore the clinical application of 64-slice spiral CT coronary angiography. Methods Forty-eight patients with suspected coronary heart disease (CHD) from June 2015 to June 2016 in our hospital were selected. All patients underwent 64-slice spiral CT coronary angiography and selective coronary angiography (CAG) Angiography results as the standard evaluation of 64-slice spiral CT coronary angiography accuracy, at the same time, different parts of coronary artery lesions and stenosis level 64-slice spiral CT coronary angiography results were analyzed. Results The accuracy of CT coronary angiography in 48 patients with suspected coronary heart disease was 93.6%, with a sensitivity of 92.8%, a specificity of 87.5%, a positive predictive value of 95.4% and a negative predictive value of 79.8%. Coronary artery proximal vascular findings were better than coronal Artery distal vascular test results; the more severe coronary artery stenosis of the blood vessels of the examination results better than the severity of coronary stenosis blood vessels test results. Conclusion 64-slice spiral CT coronary angiography is a non-invasive, simple, economical, safe and reliable method of screening coronary heart disease, coronary angiography and can be a good evaluation, and thus the interventional screening.