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目的:探讨肠内营养液间歇泵入对颅脑创伤患者胃肠功能及喂养耐受性的影响。方法:2016年1~12月选取本院神经外科收治的120例颅脑创伤患者,随机将患者等分为观察组和对照组,两组患者均行整蛋白型肠内营养制剂,对照组采用持续泵入输注,观察组采用间歇泵入输注,即输注90 min暂停150 min,每天4次,比较两组胃肠功能及喂养耐受性情况。结果:观察组胃肠功能评分均低于对照组(P<0.05),且患者胃液残留量少于对照组(P<0.05),而胃液p H值低于对照组(P<0.05)。观察组喂养耐受、7 d营养达标高于对照组(P<0.05),而胃肠应激性溃疡、消化道出血低于对照组(P<0.05)。结论:肠内营养液间歇泵入能有效提高重症颅脑损伤患者肠内营养耐受性,改善患者营养状况及胃肠功能,促进患者预后。
Objective: To investigate the effect of intermittent enteral nutrition solution on gastrointestinal function and feeding tolerance in patients with traumatic brain injury. METHODS: From January to December 2016, 120 patients with traumatic brain injury admitted to our hospital were randomly divided into two groups: observation group and control group. The patients in both groups underwent complete protein enteral nutrition. The control group received Continuous infusion pump, the observation group using intermittent pump infusion, infusion of 90 min suspended for 150 min, 4 times a day, the two groups were compared gastrointestinal function and feeding tolerance. Results: The scores of gastrointestinal function in the observation group were lower than those in the control group (P <0.05). The residual gastric juice in the observation group was less than that in the control group (P <0.05), while the p H value in the gastric juice was lower than that in the control group (P <0.05). Feeding tolerance in the observation group was higher than that in the control group on the 7th day (P <0.05), while gastrointestinal ulcer and gastrointestinal bleeding were lower than those in the control group (P <0.05). Conclusion: The intermittent pumping of enteral nutrition solution can effectively improve enteral nutrition tolerance, improve nutritional status and gastrointestinal function in patients with severe craniocerebral injury and promote prognosis.