全氟化合物(polyfluorinated compounds,PFCs)是人工合成的新型持久性有机污染物,具有广泛的生态毒理效应,其环境污染问题已成为全球关注的热点。在各种被污染的介质中,PFCs的含量往往很低,基体复杂多样,快速高效的样品前处理方法成为PFCs测定的关键。文章对近10年来PFCs测定的各种样品前处理方法和技术,包括离子对萃取、碱消化、液-液/固萃取、填充吸附剂微萃取(MEPS)和高效移液萃取(DPX)等进行了详细的总结和展望。 Polyfluorinated compounds (PFCs) are new type of persistent organic pollutants synthesized and have a wide range of ecotoxicological effects. The problem of environmental pollution has become a global concern. In a variety of contaminated media, the content of PFCs is often very low, complex and diverse matrix, fast and efficient sample preparation methods to become the key PFCs determination. In this paper, various sample preparation methods and technologies for PFCs determination including ion-pair extraction, alkaline digestion, liquid-liquid / solid extraction, packed sorbent microextraction (MEPS) and high performance liquid pipetting A detailed summary and outlook.