原发性十二指肠球部腺癌较为罕见,1977-1988年我们共收治十二指肠腺癌6例,其中只一例发生于球部,且术前误诊,现报道如下。患者女,54岁。于1986年8月8日入院。上腹部不适伴返酸、嗳气半年,近二个月出现呕吐,吐出物为隔夜食物,逐渐加重,体质明显消瘦。发病以来有间断黑便,曾在县医院上消化道钡餐透视为 Primary duodenal adenocarcinoma is rare. In 1977-1988, we treated 6 cases of duodenal adenocarcinoma, of which only one occurred in the bulb and was misdiagnosed before surgery. The report is as follows. Female patient, 54 years old. He was admitted to hospital on August 8, 1986. The upper abdominal discomfort was accompanied by acid reflux and belching for half a year. Vomiting occurred in the last two months. The vomiting was overnight food and gradually worsened. Since the onset of illness, there have been intermittent black stools.