原发性肝癌出现临床症状大多处于中晚期而以周围神经病变为首发表现的病例临床甚少,我院近2年来所见2例报告如下.例1,李家岭,男,58岁,因四肢末梢麻木,行走无力于1994年2月28日入院.患者1月前出现四肢远端麻木,感觉异常,双手握物不灵,轻微触撞即感针刺样疼痛,门诊拟“周围神经炎”治疗.症状进行性加重,双下肢呈上行性加重的感觉异常.腹部平坦.肝脾肋下未触及,右上腹轻度叩击痛,四肢远端轻度肌萎缩深浅感觉及触觉减退,双膝腱反射减弱,脑脊液蛋白定量阴性,细胞数正常,血AFP定性测定阳性,乙肝二对半测定阴性,B超示肝右后叶1.0cm×1.1cm占位性病变,呈实质性增强回声包块,CT扫描诊断原发性肝癌.入院后 The clinical symptoms of primary hepatocellular carcinoma are mostly in the middle and late stage, and the cases with peripheral neuropathy as the first manifestation are rare. In our hospital in the past 2 years, 2 cases have been reported as follows. Example 1, Li Jialing, male, 58 years old, because of limb extremities He was paralyzed and unable to walk on February 28, 1994. The patient presented with numbness in the distal extremities and felt abnormal before 1 month. Her hands were not working well. She felt acupuncture-like pain with a slight touch. The clinic wanted to treat “peripheral neuritis”. Symptoms were progressively worsened, and the lower extremities showed an upwardly aggravated sensation abnormality. The abdomen was flat. The liver and spleen were not touched by the ribs. Mild percussion pain was observed in the right upper quadrant. The distal limbs had mild muscle atrophy, deep sensation, and tactile loss. The reflex was weakened, the CSF protein was negative, the cell number was normal, the qualitative determination of blood AFP was positive, the measurement of hepatitis B two to half was negative, B ultrasound showed a 1.0cm×1.1cm occupying lesion of the right posterior segment of the liver, and it was a substantially enhanced echo mass. CT scan for diagnosis of primary liver cancer. After admission