构成难治性感染的一些有关因素:(1)致病菌对常用的抗菌药物耐药;(2)对某些致病菌缺少有效的低毒性药物;(3)人体防御功能受到损害或有免疫缺陷;(4)某些感染部位抗菌药物不易到达有效水平;(5)症状、体征隐蔽或不典型,因而未能及时诊断和治疗;(6)病人的原发病不易根治,并易反复发生感染等。 Some of the factors that make up refractory infections are: (1) pathogenic bacteria are resistant to commonly used antimicrobials; (2) lack of effective, low toxicity drugs for certain pathogens; (3) human defenses are compromised or have Immune deficiency; (4) some sites of infection of antimicrobial drugs is not easy to reach the effective level; (5) symptoms, signs hidden or atypical and thus failed to timely diagnosis and treatment; (6) the patient’s primary disease is not easy to cure, Infection and so on.