目的:对比分析内镜下非密集套扎与密集套扎对重度食管静脉曲张的治疗效果。方法:选择2013年1月~2015年12月在我院进行诊治的肝硬化并发重度食管静脉曲张患者61例,按照治疗方法的不同分为两组,A组采用内镜下非密集套扎治疗,B组采用内镜下密集套扎治疗。比较两组的治疗效果和套扎次数,并随访1年观察两组的死亡情况。结果:B组的总有效率为94.28%(33/35),明显高于A组的80.76%(21/26);B组套扎1次和2次的发生率明显高于A组,套扎3次和4次的发生率明显低于A组;B组的死亡为8.57%(3/35),明显低于A组的15.38%(4/26)。结论:对重度食管静脉曲张患者在内镜下采用密集套扎治疗的疗效明显优于非密集套扎,可以明显减少套扎次数,值得应用推广。 Objective: To compare the therapeutic effect of endoscopic non-intensive ligation and intensive ligation on severe esophageal varices. Methods: From January 2013 to December 2015 in our hospital for diagnosis and treatment of cirrhosis 61 cases of patients with severe esophageal varices, according to the different treatment methods are divided into two groups, A group by endoscopic non-intensive ligation In group B, endoscopic intensive ligation was used. The curative effect and ligation frequency of the two groups were compared, and the deaths of the two groups were observed after one year of follow-up. Results: The total effective rate in group B was 94.28% (33/35), significantly higher than that in group A (80.76%, 21/26). The incidence of ligation in group B was significantly higher than that in group A The incidence of 3 and 4 weeks was significantly lower than that of group A; the death rate of group B was 8.57% (3/35) and significantly lower than that of group A (15.38% and 4/26). Conclusion: The treatment of severe esophageal varices by endoscopic intensive ligation was significantly better than non-intensive ligation, can significantly reduce the number of ligation, it is worth to promote the application.