目的 :探讨新生儿重度窒息相关因素 ,以加强防范。方法 :对我院 10年内抢救新生儿重度窒息 83例进行相关因素分析。结果 :脐带因素 2 4例 (占 2 9% ) ,胎盘因素 15例 (占 18% ) ,胎儿窘迫 44例 (占 5 3 % )。 5分钟Apgar评分≤3分者病死率、脑损伤发生率较低 ,5分钟后行气管插管者 ,合并症发生率、病死率较高。结论 :及时诊断处置脐带异常和胎儿窘迫 ,可减少新生儿窒息 ,重度窒息的复苏关键是 5分钟内建立有效呼吸。 Objective: To investigate neonatal severe asphyxia related factors to enhance prevention. Methods: In our hospital within 10 years rescue 83 cases of severe neonatal asphyxia related factors analysis. Results: There were 24 cases of umbilical cord (29%), 15 cases of placenta (18%) and 44 cases of fetal distress (53%). 5 minutes Apgar score ≤ 3 points, the mortality rate, a lower incidence of brain injury, tracheal intubation after 5 minutes, the incidence of complications, higher mortality. Conclusion: Timely diagnosis and treatment of umbilical cord abnormalities and fetal distress, can reduce neonatal asphyxia, resuscitation of severe asphyxia the key is to establish effective breathing within 5 minutes.