[目的]探讨墨旱莲对D-半乳糖致衰小鼠免疫器官组织的影响。[方法]小鼠颈背部皮下注射D-半乳糖建立亚急性衰老模型,同时旱莲草保护组灌服旱莲草口服液,42d取胸腺、脾脏、脑制备光镜切片,H-E染色,观察组织学变化。[结果]旱莲草口服液有拮抗衰老小鼠免疫器官萎缩的作用。[结论]墨旱莲对致衰模型小鼠免疫器官有保护作用。 [Objective] To investigate the effect of Eclipta on immune organ organization of D-galactose-induced mice. [Methods] Sub-acute aging model was established by subcutaneous injection of D-galactose into mice’s neck and the Eclipta prostrata was fed with Eclipta prostrata oral liquid. The thymus, spleen and brain were taken for 42 days to prepare light microscopy and HE staining. Learn to change. [Result] Ecliptae Oral Liquid had antagonistic effect on the atrophy of immune organs in aging mice. [Conclusion] Eclipta herb has protective effect on the immune organs of mice with attenuated model.