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可泰尔为治疗上呼吸道感染的一种国家级二类新药。“用药中未见不良反应”我们於1995年11月收治眼可泰尔两天致上消化道大出血1例,现报告如下。 孟某某,男34岁,某医院药师。因发热咳嗽服可泰尔每次4粒,一日三次共两天,出现上腹部不适,恶心频繁呕吐,吐咖啡样物200～250ml,共两次。急诊入院,既往健康,有饮酒史。 入院体温36.2℃,脉搏:110次/分,血压:13.4/9.6KPa呈急性病容,略呈贫血貌,咽赤,扁桃体不肿大两肺呼吸音粗,心率110次/分律正,腹平软,剑突下压痛无反跳痛,肝脾不大。化验;血尿常规肝功均正常。胃镜结果:出血性糜烂性胃炎,病理:食道胃上皮细胞明显破坏,组织坏死和炎细胞湿润。临床诊断:药物性胃炎,上消化道出血。入院后经补液,静注西米替丁,垂体后叶素。硫糖铝等治疗两周后痊愈出院。
Kettel is a national class II drug for the treatment of upper respiratory tract infections. “No adverse reactions in the medication” We were treated in November 1995 Eye can cause digestive tract bleeding in two cases in 1 case, are as follows. Meng Moumou, male, 34 years old, a hospital pharmacist. Due to fever Cough service Ketel 4 tablets, three days a total of two days, there was abdominal discomfort, nausea frequent vomiting, spit coffee samples 200 ~ 250ml, a total of two. Emergency admission, past health, drinking history. Admission body temperature 36.2 ℃, pulse: 110 beats / min, blood pressure: 13.4 / 9.6KPa was acute disease, slightly anemic appearance, pharynx red, tonsil non-swollen lungs breath sounds thick, heart rate 110 times / Soft, xiphoid tenderness without rebound tenderness, liver and spleen is not large. Laboratory; Hematuria routine liver function are normal. Gastroscopy results: hemorrhagic erosive gastritis, pathology: significant destruction of esophageal epithelial cells, tissue necrosis and inflammatory cell wetting. Clinical diagnosis: drug-induced gastritis, upper gastrointestinal bleeding. After admission by rehydration, intravenous cimetidine, pituitrin. Sucralfate and other treatment cured two weeks after discharge.