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研究表明,全身因素可影响牙周病的发生、发展、治疗和转归,患病率较高的慢性牙周炎亦可能成为全身某些疾病的危险因素。文献报道,重度牙周病是导致或加重肾炎,甚至慢性肾功能衰竭(chronic renal failure,CRF)的危险因素,牙周致病菌及其代谢产物与肾功能衰竭时炎症反应的降低和
Studies have shown that systemic factors can affect the occurrence, development, treatment and prognosis of periodontal disease. Chronic periodontitis with higher prevalence may also be a risk factor for some systemic diseases. Reported in the literature, severe periodontal disease is caused or aggravated nephritis, and even chronic renal failure (CRF) risk factors, periodontal pathogens and their metabolites and renal failure to reduce the inflammatory response and