正常体细胞无端粒酶活性表达或很少表达[1] ,而在绝大多数肿瘤细胞和原发性高血压 (ＥＨ)患者动脉组织及外周血单个核细胞均有端粒酶活性的明显增高[2 ,3] ,且国外有研究证实外周血单个核细胞端粒酶的活性与端粒的损伤程度平行[4 ] 。但高血压患者这种端粒异常或激活是原发性还 Normal somatic cells without telomerase activity expression or rarely expressed [1], and in most tumor cells and essential hypertension (EH) patients with arterial tissue and peripheral blood mononuclear cells have a significant increase in telomerase activity [2, 3], and foreign studies have confirmed that the activity of telomerase in peripheral blood mononuclear cells parallel with the degree of damage to telomeres [4]. However, hypertensive patients with telomere abnormalities or activation are primary