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探讨医院感染病原体的构成比及其分布情况 ,为有效地开展前瞻性目标监测、加强医院感染控制提供依据。方法 :从 1999年 1月～ 2 0 0 1年 9月某院医院感染个案中抽出有明确病原体的病例进行统计。结果 :4 2 0例有病原学诊断的病例中 ,共有 5 4 4株病原体 ,真菌占 6 3.5 % ;同期发生医院感染 2 14 8例次 ,病原确诊率 2 5 .33% ,药敏试验提示新近问世的抗生素耐药率低。结论 :某院目前医院感染病原体以真菌为主 ,其次为G-菌 ,新生儿及婴幼儿以口腔白色念株菌感染最为常见 ,真菌感染治疗性用药缺少药敏指导。
To explore the constitution ratio and distribution of nosocomial pathogens, and provide basis for effective prospective target monitoring and strengthening hospital infection control. Methods : From January 1999 to September 2001, a case of nosocomial infection was collected from a hospital for statistics. RESULTS: Of the 42 cases with etiological diagnosis, 544 were pathogens and fungi accounted for 63.5%; 218 nosocomial infections occurred in the same period, and the diagnosis rate of pathogens was 25.33%. The recently introduced antibiotic resistance rate is low. Conclusion: At present, the pathogen of nosocomial infection in a hospital is mainly fungi, followed by G-bacteria. Neonatal and infants are most commonly infected with oral candida albicans, and fungal infections are lack of susceptibility to therapeutic use.