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目的：探讨影响马来丝虫对长爪沙鼠感染率的因素。方法：用含马来丝虫感染期幼虫（Ｌ３）生理盐水感染长爪沙鼠，并分别加用抗生素、葡萄糖或培养液ＲＰＭＩ１６４０，观察接种鼠的存活率、感染率和感染度。结果：用含Ｌ３生理盐水组鼠存活率为８０．９％，存活鼠感染率为６０．５％，高感染度率为４３．４％。加用抗生素组，鼠存活率为９８．８％，存活鼠感染率为５２．９％，高感染度率为３０．６％。加用葡萄糖或ＲＰＭＩ１６４０组，鼠存活率（分别为９８．０％和９１．２％）、感染率（分别为６８．８％和６７．７％）和高感染度率（分别为５０．０％和５１．６％）均较高。长爪沙鼠感染马来丝虫浙江株（６代），存活鼠感染率和高感染度率均较贵州株（３１代）高。结论：加用抗生素能提高感染鼠存活率，但其感染率和感染度降低。加用葡萄糖和ＲＰＭＩ１６４０，能提高感染鼠存活率、感染率和感染度。长爪沙鼠对浙江株（６代）较贵州株（３１代）易感。
Objective: To explore the factors that affect the infection rate of malayian worm on Mongolian gerbils. Methods: Meriones unguiculatus was infected with larvae of larvae infected with Malay worm (L3), and antibiotics, glucose or RPMI1640 were added respectively to observe the survival rate, infection rate and infection rate. Results: The survival rate of mice with L3 saline group was 80.9%, the survival rate of infected mice was 60.5%, and the high infection rate was 43.4%. With the antibiotic group, the survival rate of mice was 98.8%, the survival rate of infected mice was 52.9%, and the rate of high infection was 30.6%. Survival rates of mice (98.0% and 91.2%, respectively), infection rates (68.8% and 67.7%, respectively) and high infection rates (50.0 % And 51.6%) were higher. Mongolian gerbils infected Zhejiang (6 generations), surviving mice infection rate and high infection rate than Guizhou strain (31 generations) high. Conclusion: Adding antibiotics can improve the survival rate of infected mice, but the infection rate and the infection rate decrease. Plus glucose and RPMI1640, can improve the survival rate of infected mice, infection rates and degree of infection. Mongolian gerbils are more susceptible to Zhejiang strain (6 generations) than Guizhou strain (31 generations).