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目的探讨急性白血病院内感染情况。方法调查6年来就诊的急性白血病并发院内感染的临床特点,并对感染部位、病原菌以及易感因素进行分析。结果并发院内感染以G-菌为主,但近几年真菌感染的比例明显上升,感染部位以肺、口、咽部多见,感染与患者的年龄、外周白细胞、住院时间以及激素的应用有关,而与患者性别、白血病类型无关。结论针对急性白血病院内感染的易感因素,采用有效的预防及抗感染措施,并减少粒细胞缺乏时间是治疗的关键。
Objective To investigate the nosocomial infection in acute leukemia. Methods The clinical features of acute leukemia complicated with nosocomial infection in the past 6 years were investigated. The infection site, pathogens and susceptibility factors were also analyzed. The results of concurrent nosocomial infections with G-bacteria, but in recent years the proportion of fungal infections increased significantly, the infection of the lungs, mouth, pharynx more common, the infection and the patient’s age, peripheral leukocytes, hospitalization and hormone application , But not with the patient’s gender, type of leukemia. Conclusion According to the susceptible factors of nosocomial infection in acute leukemia, effective preventive and anti-infective measures and the reduction of agranulocytosis are the key points of treatment.