建立了高效快速的液相色谱法对线性烷基苯磺酸钠(linear alkylbenzene sulfonates,LAS)的分离测定方法.采用Symmetry C8柱分离,检测波长为224 nm.探讨了流动相中甲醇和盐的种类等对LAS分离效果的影响;优化后的LAS分离条件为:流动相中V(甲醇)∶V(水)=77∶23且含有0.5 mmol/L无水CH3COONa,流速为0.5 mL/min,LAS同系物的线性范围为0.20～23.00 mg/L,其相对标准偏差均小于5%.将该方法用于实际水样中LAS的分析,结果满意. A rapid and sensitive HPLC method was developed for the determination of linear alkylbenzene sulfonates (LAS) using a Symmetry C8 column with a detection wavelength at 224 nm.The effects of methanol and salt on the mobile phase The optimum conditions for the separation of LAS were as follows: V (methanol): V (water) = 77:23 in the mobile phase and 0.5 mmol / L anhydrous CH3COONa at a flow rate of 0.5 mL / min, The linear range of LAS homologues was 0.20-23.00 mg / L, and the relative standard deviations were all less than 5%. The method was applied to the analysis of LAS in real water samples with satisfactory results.