[目的]探讨Cook子宫颈扩张球囊在晚期妊娠孕妇促宫颈成熟中的应用价值.[方法]选择2014年1月至2017年1月本院诊治的有引产指征的患者189例,按照处理方式的不同分为 Cook 子宫颈扩张球囊组(COOK组)、地诺前列酮组和缩宫素组,每组63例.比较各组促宫颈成熟效果和阴道分娩率.[结果]各组在引产前的宫颈Bishop评分比较差异无统计学意义(P >0.05);COOK 组患者经 COOK 宫颈扩张球囊处理后宫颈Bishop评分为(4.3±1.9)分,较引产前显著升高(P 0.05);COOK组中51例患者自然分娩,12例行剖宫产,自然分娩率为80.95%;COOK 组与地诺前列酮组的自然分娩率(76.19%)比较差异无统计学意义(P >0.05),但均显著高于缩宫素组的58.73% (P 0.05).In the COOK group,the cervical Bishop score was (4.3±1.9)after Cook cervical dilatation balloon treatment,which was significantly higher than that before induction of labor (P 0.05).In the Cook group,51 cases of natural childbirth,and 12 cases of cesarean section;the vaginal delivery rate was 80.95%.The rate of natural childbirth in the dinoprostone group was 76.19%,which was not significant different com-pared to the COOK group (P >0.05),however,they both were significantly higher than that in the oxytocin group (58.73% P<0.05).[Conclusion]Cook cervical dilatation balloon is used as a mechanical method to promote cervical ripe-ning,which can increase vaginal delivery rate significantly with high safety levels and fewer complications.It is an ideal method for promoting cervical ripening in late-stage pregnancy.