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美尼尔氏病是以眩晕为主,伴随耳聋、耳鸣、恶心呕吐等症状的常见病。其病因至今未确定,多数学者支持内耳神经血管障碍主张,以致内耳膜迷路水肿。我院耳鼻咽喉科晕眩小组从1982年6月至1985年6月应用盐酸培他啶治疗美尼尔氏病共计65例,取得良好效果,未发现不良反应。盐酸培他啶又名抗眩啶、甲胺乙吡啶,它是一种组织胺药物,它具有明显的扩张微循环毛细血管的功能,增加耳蜗和前庭的血流量,作用较为持久,改善内耳循环,减除内耳水肿,消除眩晕。还能抑制组织胺释放,产生抗过敏的作用。我们应用的方法是:住院患者用盐酸培他啶氯化钠注射液,每天静脉滴注500ml,十次为一疗
Meniere’s disease is mainly dizziness, accompanied by deafness, tinnitus, nausea and vomiting and other symptoms of common disease. The etiology has not yet been determined, most scholars support the claim of the inner ear neurovascular disorders, resulting in edema of the inner ear. Our hospital otolaryngology department dizziness group from June 1982 to June 1985 application of methotrexate hydrochloride treatment of Meniere’s disease a total of 65 cases, and achieved good results, no adverse reactions were found. Hydropic acid hydrochloride, also known as anti-dizziness pyridine, methylamine, which is a histamine drugs, it has the obvious expansion of microcirculation capillary function, increased cochlear and vestibular blood flow, the role of more durable and improve the inner ear circulation , Reduce ear edema, eliminate dizziness. Can also inhibit histamine release, resulting in anti-allergic effects. Our method is: hospitalized patients with hydrochloric acid injection of sodium pentital hydrochloride, intravenous infusion of 500ml daily, ten times for a treatment