论文部分内容阅读
2月龄雌性SD大鼠进行十周大强度跑台运动后出现运动性动情周期抑制现象,以模拟长期耐力运动训练后女运动员出现的运动性闭经病理现象。比色法、放免法测定骨代谢生化标志物指标,单光子吸收法测定股骨、胫骨的骨密度,三点弯曲试验测定股骨、胫骨的生物力学特征。结果发现,与对照组相比,运动性动情周期抑制雌性大鼠骨形成指标显著性降低,骨吸收指标显著性升高,胫骨的骨密度显著性降低,股骨、胫骨的最大载荷、弹性载荷均显著低于对照组。结果揭示十周大强度跑台运动致运动性动情周期抑制雌性大鼠骨的支持功能降低。
The 2-month-old female Sprague-Dawley (SD) rats exhibited inhibition of exercise-induced estrous cycle after a ten-week intensive treadmill exercise to simulate the phenomenon of motor amenorrhea in female athletes after long-term endurance training. Colorimetry and radioimmunoassay were used to determine the biochemical markers of bone metabolism. The bone density of the femur and tibia was determined by single-photon absorption method. The biomechanical characteristics of the femur and tibia were measured by three-point bending test. The results showed that, compared with the control group, exercise-induced estrous cycle inhibited female rats significantly decreased bone formation index, bone resorption index was significantly increased, significantly lower tibia bone mineral density, femur, tibia maximum load, elastic load Significantly lower than the control group. The results revealed that ten weeks of intensive treadmill exercise resulted in decreased motility of the estrous cycle-inhibited female rat bone support function.