用二丁基氧化锡与苯磺酸、甲磺酸反应制备了两种新的有机锡化合物——二丁基锡(IV)磺酸酯.以二丁基锡(IV)磺酸酯作催化剂,合成了一系列缩醛(酮),并通过正交实验,优化了有机锡催化缩醛(酮)合成反应的反应条件.实验表明该催化反应产率高,反应时间短,催化剂用量少且能回收再利用. Two new organotin compounds, dibutyltin (IV) sulfonate, were prepared by the reaction of dibutyltin oxide with benzenesulfonic acid and methanesulfonic acid. Using dibutyl tin (IV) sulfonate as catalyst, Series acetals and ketones were synthesized and the reaction conditions of the organo-tin catalyzed acetal (ketone) synthesis were optimized by orthogonal experiments.The experimental results show that the catalytic reaction has high yield, short reaction time, small amount of catalyst and can be recycled use.