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目的分析探讨血必净对消化道恶性肿瘤相关性腹膜炎患者白细胞计数、C反应蛋白、降钙素原水平的影响。方法 80例消化道恶性肿瘤相关性腹膜炎患者,随机分为观察组和对照组,每组40例。其中对照组采用单纯的抗生素干预治疗,观察组则在对照组基础上予以血必净注射液治疗。观察两组患者用药前后白细胞计数、C反应蛋白、降钙素原水平的变化情况。结果观察组的总有效率为95.0%,对照组的总有效率为72.5%,观察组总有效率高于对照组,差异具有统计学意义(P<0.05);治疗后两组患者的白细胞计数、C反应蛋白、降钙素原水平均有明显改善,差异均具有统计学意义(P<0.05)。结论血必净对消化道恶性肿瘤相关性腹膜炎患者白细胞计数、C反应蛋白、降钙素原水平方面的临床疗效显著,并且能有效改善患者在发病期间出现的发热、腹痛、腹胀等不适症状,不良反应较少,值得临床应用和推广。
Objective To investigate the effect of Xuebijing on the white blood cell count, C-reactive protein and procalcitonin in patients with gastrointestinal cancer associated peritonitis. Methods 80 patients with gastrointestinal malignant tumor associated peritonitis were randomly divided into observation group and control group, 40 cases in each group. The control group was treated with simple antibiotics, and the observation group was treated with Xuebijing injection on the basis of the control group. The changes of leukocyte count, C-reactive protein and procalcitonin before and after treatment were observed in both groups. Results The total effective rate was 95.0% in the observation group and 72.5% in the control group, and the total effective rate in the observation group was higher than that in the control group (P <0.05). The white blood cell count , C-reactive protein, procalcitonin levels were significantly improved, the differences were statistically significant (P <0.05). Conclusion Xuebijing has significant clinical effect on white blood cell count, C-reactive protein and procalcitonin in patients with gastrointestinal cancer-related peritonitis, and can effectively improve the symptoms of fever, abdominal pain, bloating and other discomfort during the onset of the disease, Less adverse reactions, it is worth clinical application and promotion.