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目的:针对不同剂量丙种球蛋白联合阿司匹林治疗小儿川崎病的临床疗效果进行研究分析。方法:收集本院自2012年3月~2016年3月这一期间收治的60例川崎病患儿作为本次的研究对象,根据患者的就诊序列号将其随机分为两组,每组各平均纳入30例患者,其中一组为观察组,该组使用大剂量丙种球蛋白联合阿司匹林进行治疗,另外一组为对照组,该组使用小剂量丙种球蛋白联合阿司匹林进行治疗,最后针对两组患者的治疗效果进行对比分析。结果:经过相应的治疗后,两组患者的各项血清指标均得到有效改善,但是观察组的改善情况优于对照组患者,两组对比具有显著性差异,P<0.05。在治疗总有效率的对比中,观察组高于对照组,两组对比具有显著性差异,P<0.05。结论:针对川崎病患儿大剂量、少次给予丙种球蛋白联合阿司匹林治疗具有较好的应用效果,优于小剂量、多次的治疗效果,值得广泛推广应用。
Objective: To study the clinical effects of different doses of gamma globulin combined with aspirin in the treatment of pediatric Kawasaki disease. Methods: Sixty children with Kawasaki disease who were admitted to our hospital from March 2012 to March 2016 were selected as the subjects of this study. Patients were randomly divided into two groups according to their visiting serial number An average of 30 patients were enrolled, one of them in the observation group, which was treated with high-dose gamma-globulin plus aspirin and the other one in the control group, which was treated with low-dose gamma globulin plus aspirin. Finally, Patient’s treatment effect comparative analysis. Results: After the corresponding treatment, the serum indexes of both groups were all improved effectively. However, the improvement of the observation group was better than that of the control group. There was significant difference between the two groups (P <0.05). In the total effective rate of treatment, the observation group was higher than that of the control group, with significant difference between the two groups (P <0.05). Conclusion: The Kawasaki disease in children with high dose, less administration of gamma globulin combined with aspirin treatment has better application effect, better than low-dose, multiple treatment, it is worthy of wide application.