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通过用流式细胞仪检测不同临床分期的乳腺癌患者术前术后外周血中多项免疫指标:CD+3,CD+4,CD+8,CD+19,CD+16的淋巴细胞及rδT细胞所占比例,了解不同临床分期的患者免疫功能状态及其术前术后的变化。结果表明:乳癌患者免疫功能普遍紊乱,特别是细胞免疫功能明显低下,临床分期越晚,这种表现越明显,而术后患者免疫功能有一定改善,因而,流式细胞仪测定上述多项免疫指标,对了解乳腺癌患者病情发展及预后转归有一定的临床意义。
The flow cytometry was used to detect the preoperative and postoperative peripheral blood levels in multiple clinical stages of breast cancer patients: CD+3, CD+4, CD+8, CD+19, CD+16 lymphocytes, and rδT cells, to understand the different clinical stages The patient’s immune function status and its changes before and after surgery. The results showed that the immune function of breast cancer patients was generally disordered, especially the cellular immune function was significantly lower. The later the clinical stage was, the more obvious this performance was, and the patient’s immune function was improved after the operation. Therefore, the above-mentioned multiple immunity was measured by flow cytometry. Indicators have a certain clinical significance for understanding the progression of breast cancer patients and prognosis.