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呼吸道粘膜的防御机能,除了粘膜上皮的完整性,分泌物的覆盖,酸碱度,酶类以及纤毛运动的清除作用外,分泌型免疫球蛋白A(SIgA)参与呼吸道粘膜的免疫功能,值得重视。SIgA在局部粘膜有强大的抗细菌、抗病毒作用,能保护呼吸道粘膜免受细菌和病毒的侵犯。South曾证实在SIgA缺乏或低下者,易患慢性上呼吸道感染,表明SIgA在局部免疫系统的重要性。但究竟SIgA在呼吸道粘膜起什么作用呢?现浅述于下:
Respiratory mucosal defense function, in addition to mucosal epithelial integrity, secretions cover, pH, enzymes and ciliary motility removal, secretory immunoglobulin A (SIgA) involved in respiratory tract mucosal immune function, it is worth attention. SIgA in the local mucosa has a strong anti-bacterial, anti-viral effect, can protect the respiratory tract mucosa from bacteria and viruses. South has demonstrated that SIgA deficiency or low susceptibility to chronic upper respiratory tract infection indicates the importance of SIgA in the local immune system. But what is the role of SIgA in the respiratory mucosa now? Now under the next: