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已知闭经后的雌激素减少,钙摄取量下降,长期卧床或宇宙飞行的失重等种种原因可致骨或肌肉萎缩;实验方面也有报告,如大鼠摘去卵巢,限制摄钙,用石膏固定使后肢制动及吊起尾部使后肢失重,导致骨重量或钙含量及骨骼肌重量显著下降。运动不足和废用引起骨和肌肉萎缩的机制之一是骨和肌肉血流量减少。反之,运动和训练引起骨和肌肉血流量增加,骨和肌肉机能低下之恢复可能与此有关。
Known amenorrhea after estrogen reduction, decreased calcium intake, long-term bed or space flight weight loss and other causes bone or muscle atrophy; experimental aspects have also been reported, such as rats pick the ovaries, limit the intake of calcium, fixed with plaster Braking the hindlimb and lifting the hind limb to lose weight results in a significant decrease in bone or calcium content and skeletal muscle mass. One of the mechanisms of under-exercising and disuse-induced bone and muscle atrophy is reduced bone and muscle blood flow. Conversely, exercise and training lead to increased bone and muscle blood flow, and recovery of bone and muscle dysfunction may be related to this.