瑞舒伐他汀是3-羟-3-甲戊二酰辅酶A(HMG-CoA)转变成胆固醇的前体甲羟戊酸过程中的限速酶HMG-CoA还原酶抑制剂,临床应用广泛。近年来国内有文献报道,本品可致横纹肌溶解,现概述如下:岳慧杰等报道,患男,68岁,因脑梗塞、高血压及糖尿病给予瑞舒伐他汀10mg口服,qn,6天后患者突发左侧肢体无力,随之出现胸口针刺样疼痛,查肌酸 Rosuvastatin is a rate-limiting enzyme HMG-CoA reductase inhibitor in the conversion of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) into a precursor of melatonin, which is widely used clinically. In recent years, domestic literature reports that this product can cause rhabdomyolysis, are summarized as follows: Yue Huijie et al reported that suffering from male, 68 years old, due to cerebral infarction, hypertension and diabetes given rosuvastatin 10mg orally, qn, 6 days after the patient suddenly Fat left limb weakness, followed by chest acupuncture pain, check creatine