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目的探讨纳络酮联合醒脑静治疗急性酒精中毒患者的临床效果。方法选取2013年1月至2015年1月来阜新矿业集团总医院就诊的74例酒精中毒患者为研究对象,按随机数字表法将其分为观察组和对照组,各37例。对照组患者静脉滴注盐酸纳洛酮注射液,观察组患者在对照组基础采用醒脑静注射液进行治疗,比较两组患者的临床疗效、清醒时间、症状消失时间及血压恢复情况。结果观察组患者治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组患者的清醒时间、症状消失时间均明显短于对照组,差异均有统计学意义(均P<0.05);观察组患者血压恢复正常率明显高于对照组,差异有统计学意义(P<0.05)。结论纳络酮联合醒脑静治疗急性酒精中毒患者临床疗效明显,可促使患者早日康复。
Objective To investigate the clinical effect of naloxone combined with xingnaojing in treating patients with acute alcoholism. Methods Totally 74 alcoholic patients who visited Fuxin Mining Group General Hospital from January 2013 to January 2015 were selected as study subjects and divided into observation group and control group according to random number table method, 37 cases in each group. Patients in the control group were treated with intravenous naloxone hydrochloride injection. Patients in the observation group were treated with xingnaojing injection on the basis of the control group. Clinical efficacy, awake time, disappearance of symptoms and recovery of blood pressure were compared between the two groups. Results The total effective rate of treatment in observation group was significantly higher than that in control group (P <0.05). The awake time and the disappearance of symptoms in observation group were significantly shorter than those in control group (P <0.05) P <0.05). The recovery rate of blood pressure in the observation group was significantly higher than that in the control group (P <0.05). Conclusion Naloxone combined with Xingnaojing in patients with acute alcoholism clinical efficacy significantly, can promote the early recovery of patients.