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目的探讨镜体直接分离建立后腹腔(IUPU)与自制气囊2种建腔方式对单孔单通道后腹腔镜肾囊肿手术患者血清C反应蛋白(CRP)、白细胞介素-6(IL-6)、血糖和皮质醇水平的影响。方法将208例肾囊肿患者随机分为A组和B组各104例。所有患者完善相关检查、给予对症治疗后择期行单孔单通道后腹腔肾囊肿手术治疗。A组采用自制气囊法建腔,B组选择IUPU法建立后腹腔。术后给予分级护理,检测并比较2组临床疗效和治疗前后血清CRP、IL-6、血糖和皮质醇水平。结果 A组总有效率明显高于B组(P<0.05)。治疗前2组血清CRP、IL-6、空腹血糖和皮质醇水平差异均无统计学意义(P>0.05)。治疗后2组CRP、IL-6、空腹血糖和皮质醇水平均高于治疗前,且A组增高幅度小于B组,差异均有统计学意义(P<0.05)。结论自制气囊法治疗肾囊肿对手术创伤、术后应激的影响较IUPU建腔较小,值得临床推广应用。
Objective To investigate the relationship between the levels of serum C-reactive protein (CRP), interleukin-6 (IL-6) and interleukin-6 (IL-6) in patients undergoing single- , Blood sugar and cortisol levels. Methods 208 cases of renal cysts were randomly divided into A group and B group of 104 cases. All patients to improve the relevant examination, given symptomatic treatment after elective single-hole single-lane retroperitoneal renal cyst surgery. A group using homemade balloon method to build cavity, B group choose IUPU method to establish the posterior abdominal cavity. Grading nursing was given after operation. The clinical curative effect and serum CRP, IL-6, blood glucose and cortisol levels before and after treatment were detected and compared between the two groups. Results The total effective rate in group A was significantly higher than that in group B (P <0.05). There was no significant difference in serum CRP, IL-6, fasting blood glucose and cortisol levels between the two groups before treatment (P> 0.05). The levels of CRP, IL-6, fasting blood glucose and cortisol in the two groups after treatment were all higher than those before treatment, and the increase in group A was less than that in group B, the difference was statistically significant (P <0.05). Conclusion The self-made balloon method for the treatment of renal cysts on the surgical trauma, post-operative stress than the IUPU built cavity smaller, worthy of clinical application.