头孢拉定是一种稳定性好、刺激性小在临床上广泛使用的唯一可供口服和注射的头孢菌素,头孢拉定的抗菌作用,药物动力学及临床应用与头孢氨苄基本相同而且对β内酰胺酶更稳定,毒性低,治疗指数大。应用后血浓度较高,蛋白结合率6％,能广泛地分布至各组织中。不良反应少,对肾毒性尤低。因此头孢拉定在治疗和预防多种感染中具有较高疗效。 Cephradine is a stable, less irritating small clinically used only for oral and injectable cephalosporins, cefradin antibacterial effect, pharmacokinetics and clinical applications and cephalexin basically the same and β-lactamase More stable, low toxicity, therapeutic index. After application of high blood concentration, protein binding rate of 6%, can be widely distributed to various tissues. Adverse reactions, especially low on renal toxicity. Cefradine therefore has a high efficacy in the treatment and prevention of multiple infections.