肺肿瘤内出现空洞已有一些文章和病例报告。Dodd和Boyle复习了M.Dandlers-on医院6729例病人连续的胸部X线照片,估计原发性肺肿瘤自发性空洞的发生率为9％,转移性肺结节为4％。然而,他们没有报告任何发生于化疗后的空洞病例。有材料提到继发于治疗后肺转移灶的个别病例。我们报告了三例肺转移肿瘤的病人,X线照片表明空洞是化疗的直接反应。 There are several articles and case reports of holes in lung tumors. Dodd and Boyle reviewed consecutive chest radiographs of 6729 patients in M. Dandles-on Hospital. The incidence of spontaneous cavitation in primary lung tumors was estimated to be 9% and metastatic pulmonary nodules was 4%. However, they did not report any empty cases that occurred after chemotherapy. There are materials mentioning individual cases secondary to post-treatment lung metastases. We reported three patients with metastatic lung tumors. X-rays showed that the void was a direct response to chemotherapy.