男性,26岁,待业青年。1984年1月5日因发热13天,尿黄8天入院。入院前13天低热伴畏寒,全身不适,服感冒药未果。第5天高热,寒战,头痛,疲倦,纳差,尿如浓茶,眼黄。第8天某院诊为黄疸型病毒性肝炎,按肝炎治疗。发热不退在40℃左右,间有谵语,治疗5天症状未减,乃转我院治疗。入院时体温40.5℃,脉搏128次,呼吸22次,血压100/70,神志清,检查合作,呼吸平顺,皮肤及巩膜深度黄染,未见出血点及皮疹。眼结合膜充血,瞳孔等圆,咽充血(+)。心搏规整,未闻杂音。腹软,无压痛,无反跳痛,肝上界在第6肋间,右锁骨中线肋下4cm,剑突下6cm,质Ⅰ～Ⅱ°,表面光滑无触痛。脾于肋下未触及,无腹水征。双下肢无浮肿。脑膜刺激征阴性,病理神经反射阴性。住院经使用氯霉素, Male, 26 years old, unemployed youth. January 5, 1984 due to fever for 13 days, 8 days urine yellow admission. Low fever with chills, general malaise 13 days before admission, unsuccessful cold medicine. Day 5 High fever, chills, headache, tiredness, anorexia, urine such as strong tea, eye yellow. On day 8, a hospital diagnosed with jaundice-type viral hepatitis, according to hepatitis treatment. Refired fever at about 40 ℃, between a language, treatment for 5 days did not reduce the symptoms, is transferred to our hospital. Admission temperature 40.5 ℃, pulse 128 times, breathing 22 times, blood pressure 100/70, conscious mind, check cooperation, smooth breathing, skin and sclera depth of yellow dye, no bleeding and rash. Eye combined with membrane congestion, pupil and other round, pharyngeal congestion (+). Heartbeat, unheard noise. Abdominal soft, no tenderness, no rebound pain, the upper boundary of the liver in the 6th intercostal space, right subclavian midline rib 4cm, 6cm below the xiphoid, quality Ⅰ ~ Ⅱ °, smooth surface without tenderness. Spleen in the ribs did not touch, no signs of ascites. No lower extremity edema. Negative meningeal irritation, negative pathological reflex. After hospitalized with chloramphenicol,