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靶器官的淋巴样细胞浸润是许多自身免疫病的特征。原发性Sjogren氏综合征(1°ss)的特点是在唾液腺中有淋巴样细胞浸润和产生自身抗体,因此单独研究患者PBL是不能揭露发病原因的。本文研究1°ss患者唾液腺浸润的淋巴细胞(SGL)及末梢血淋巴细胞(PBL)。共检查14例1°ss患者活检(SGL)材料,发现每一病例中,大多数的淋巴细胞为Leu 3 a亚群T细胞(Leui;Leu4),约占50～75％。而Leu 2 a
The lymphoid infiltration of target organs is characteristic of many autoimmune diseases. Primary Sjogren’s Syndrome (1 ° ss) is characterized by lymphoid infiltrates and autoantibodies in the salivary glands, and therefore the study of patients with PBL alone can not reveal the cause of the disease. This article investigates salivary gland infiltrating lymphocytes (SGLs) and peripheral blood lymphocytes (PBLs) in 1 ° ss patients. A total of 14 patients with 1 ° ss biopsy (SGL) were examined and found that in each case, most of the lymphocytes were Leu 3 a subpopulation T cells (Leui; Leu4), accounting for about 50-75%. Leu 2 a