镰状细胞病常见于中、西非,地中海地区,是一种遗传性血红蛋白分子病。近年国内已见少数病例报道。本文就作者1979～1981年在多哥洛美工作期间所见76例进行临床分析。76例中,男43例,女33例;年龄最小12岁,最大85岁。幼年起病者常病情较重。本病临床表现复杂,但以关节疼痛最常见,常反复、绵延终生。本组有关节疼痛66例(86.84％), Sickle cell disease is common in Central and West Africa, the Mediterranean region, is a hereditary hemoglobin disease. In recent years, a few cases have been reported in China. This article presents the clinical analysis of 76 patients seen during the period 1979-1981 in Lome, Togo. 76 cases, 43 males and 33 females; the youngest 12 years old, maximum 85 years old. Young patients are often more serious illness. The clinical manifestations of the disease complex, but the most common joint pain, often repeated, lasting life. The group had 66 cases of joint pain (86.84%),