河南医学院第一附属医院肿瘤科临床实践证明,采用平阳霉素、消瘤芥、冬凌草联合用药(暂定名为联药1号)在治疗食管癌方面取得了明显效果。但对其抑癌机理尚缺乏研究。为弄清本药抑癌机制,实验采用109食管癌株在培养瓶内用药,先用冲击量(人体用药量的10倍),4小时后改用维持量(人体用药量的3倍),于四日内,依次每日取材,然后以Pearse The First Affiliated Hospital of Henan Medical College Department of Oncology clinical practice has proved that the use of pingyangmycin, tumor mustard, combination of rubescens (tentatively named Liangyou No. 1) in the treatment of esophageal cancer has achieved remarkable results. However, its tumor suppressor mechanism is still lack of research. To clarify the tumor suppressor mechanism, the experiment using 109 esophageal cancer strains in the bottle medication, first with the impact of the amount (10 times the human dose), 4 hours later to maintain the amount (3 times the body dose) In four days, followed by a daily draw, and then to Pearse