目的探讨晨笛网压缝合术(Chendi netlike compression suture,CNCS)在难治性产后出血中常规方法治疗无效后替代子宫切除术的有效性。方法回顾性分析采用CNCS对5例难治性产后出血患者的治疗,评价其疗效及安全性。结果 5例患者行CNCS后,子宫活动性出血5~15 min停止,阴道无流血后关腹,均成功保留子宫。MRI检查显示:术后4 d宫壁见散在点状信号,术后46d宫壁肌层信号均匀,宫内膜线清晰;超声检查显示:术后42d宫壁肌层回声均匀,复旧形态良好;随访结果为:5例患者术后42 d复查,恶露均已净,停止哺乳后1~2个月经恢复正常。其中1例患者于术后20个月再次妊娠,29个月后经剖宫产诞下一健康女婴。结论 CNCS在难治性产后出血治疗中具有重要应用价值,对经常规药物及手术治疗无效患者,应果断选择CNCS进行急救以挽救患者子宫。 Objective To investigate the effectiveness of the Chendi netlike compression suture (CNCS) in the treatment of refractory postpartum hemorrhage in the replacement of hysterectomy by conventional methods. Methods The clinical data of 5 patients with intractable postpartum hemorrhage treated with CNCS were retrospectively analyzed to evaluate their efficacy and safety. Results After 5 patients underwent CNCS, the uterine active bleeding stopped for 5 ~ 15 min and the vagina was closed without blood flow, all of which successfully retained the uterus. MRI examination showed that on the 4th day after operation, scattered signals appeared on the parietal wall. The signal on the parietal myometrium was uniform and the endometrial line was clear on the 46th day after operation. Ultrasonography showed that the parietal muscular wall had a uniform echogenicity and good shape after the 42 days. The follow-up results were as follows: 5 patients were reviewed after 42 days, and the lochia were all net. One to two months after stopping breast-feeding returned to normal. One patient was pregnant again 20 months after surgery and a healthy baby girl was delivered by cesarean section after 29 months. Conclusion CNCS plays an important role in the treatment of intractable postpartum hemorrhage. For those patients who are ineffective by conventional drugs and surgical treatment, CNCS should be decisive for first aid to save the patient’s uterus.