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抑肽酶是自然存在的丝氨酸蛋白酶抑制剂,可抑制血管舒缓素和纤维蛋白溶酶,有关抑肽酶对粘连形成的作用早有研究,但无结论。作者采用测定羟脯氨酸(OHP)内容物来观察抑肽酶的作用,并研究其对局部纤溶活性的影响。取92只Wistar鼠,6只鼠用于测定粘连形成方法,6只鼠测定OHP
Aprotinin is a naturally occurring serine protease inhibitor that inhibits both kallikrein and plasmin. The role of aprotinin on adhesion has long been studied, but no conclusion has been reached. The authors used the assay of hydroxyproline (OHP) content to observe aprotinin and investigated its effect on local fibrinolytic activity. Ninety-two Wistar rats, six rats were used to determine adhesion formation and six rats were tested for OHP