患者,女,56岁。因服敌杀死250ml、毒杀芬150ml后昏迷12小时入院。患者服药后半小时曾在当地医院诊断为有机磷农药中毒,以清水20 000 ml洗胃,并给予阿托品、解磷定治疗10小时(具体用量不详),症状无缓解,送入我院急诊科。查体:体温 39.2℃,脉搏触不到,呼吸30次/min,血压测不到,深昏迷,面色潮红,肢体温暖、干燥,四肢抽搐,双侧瞳孔等大等圆,直径约9 mm,对光反射消失,双肺呼吸音粗糙,可闻及湿性罗音,心率159次/min,律不齐。立即予以血液灌流治疗。在血液灌流过程中出现心跳停止,经给予胸外心脏按压及肾上腺素1mg、尼或刹米0.75、回苏灵8mg、洛贝林3mg静推等处理,2分钟后心跳恢复。血液灌流术历时6小时。术后查体:体温35.5℃,血压仍测不到,浅昏迷,双瞳孔直径8mm,对光反射存在,四肢仍有抽搐,双肺闻及中量湿 Patient, female, 56 years old. Due to serve the enemy to kill 250ml, poisoning Fen 150ml coma 12 hours after admission. Half an hour after taking the patient was diagnosed in the local hospital organophosphate pesticide poisoning, lavage with water 20 000 ml, and given atropine, Phosphorus Defluoridation for 10 hours (the specific amount is unknown), the symptoms did not ease, into our hospital emergency department . Examination: body temperature 39.2 ℃, pulse touch, breathing 30 beats / min, blood pressure can not be measured, deep coma, flushed, warm limbs, dry limbs convulsions, bilateral pupil and other large round, diameter of about 9 mm, On the disappearance of light reflection, lung breath sounds rough, can be heard and wet rales, heart rate 159 times / min, irregularities. Immediately hemoperfusion treatment. During the process of hemoperfusion, the heartbeat stopped. The patients were given extrathoracic cardiac pressure and epinephrine 1mg, Nepalese or Brake 0.75, Hui Su Ling 8mg and Lobeline 3mg, and the heartbeat recovered after 2 minutes. Hemoperfusion lasted 6 hours. Postoperative examination: body temperature 35.5 ℃, blood pressure is still undetectable, shallow coma, double pupil diameter 8mm, the presence of light reflexes, limbs still have convulsions, lungs smell in the amount of wet