发展避孕药的最终目的是要设计出一种方法,具有100％的避孕效果、无毒性表现、受用者欢迎并只须最小的维持量。迄今为止,口服雌激素——孕激素复合剂是最有效的避孕手段,然而随着应用经验的增加,看到了越来越多的副作用。为了避免这些副作用,逐渐调整了激素药物的比率。一种极端是每月除了极少几天外,完全不用孕激素(序贯法)。另一种极端是完全不用雌激素(微剂片剂)。一般说,在这些制剂里不用 The ultimate goal of developing contraceptives is to devise a method with 100% contraceptive effectiveness, non-toxic performance, and welcome by the user with minimal maintenance. To date, oral estrogen-progestin combination is the most effective contraceptive method, however, with the increasing application experience, more and more side effects are seen. In order to avoid these side effects, gradually adjust the hormone drug ratio. One extreme is no progestin (Sequencing) at all but a few days a month. The other extreme is the complete absence of estrogen (micro-agent tablets). In general, not in these preparations