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目的分析成人still病的临床特点、实验室检查结果、治疗方法及预后,提高对该病的认识。方法回顾性分析我科自2008年到2012年共收治的成人still病15例的临床表现、实验室检查结果。结果发热、皮疹、关节酸痛是成人still的主要临床表现,非甾体类消炎镇痛药物及糖皮质激素或/(和)免疫抑制剂是有效的治疗方法。结论成人Still病临床表现多样,临床多以发热、皮疹、关节症状为主要表现,实验室检查缺乏特异性,诊断需除外其他导致发热的疾病,多数患者对糖皮质激素反应良好,部分患者需要同时加用免疫抑制剂或生物制剂。
Objective To analyze the clinical characteristics of adult still disease, laboratory test results, treatment and prognosis, and to improve their understanding of the disease. Methods Retrospective analysis of clinical manifestations and laboratory findings of 15 cases of adult still disease in our department from 2008 to 2012 were retrospectively analyzed. Results Fever, skin rashes and joint pain were the main clinical manifestations of adult still. Non-steroidal anti-inflammatory analgesics and glucocorticoids or / and immunosuppressive agents were effective treatments. Conclusion The clinical manifestations of Still’s disease in adults are diverse. The clinical manifestations are mostly fever, rash and joint symptoms. Laboratory tests lack specificity. Other diseases that cause fever are excluded. Most patients respond well to glucocorticoids and some patients need both Plus use of immunosuppressive agents or biological agents.