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对２３例血管母细胞瘤进行临床病理免疫组化观察，并与血管母细胞性脑膜瘤和脑膜的血管外皮瘤作比较。结果发现，２３例血管母细胞瘤均发生于小脑，内皮细胞ＦⅧ阳性，间质细胞和内皮细胞Ｖｉｍ均为阳性；５例血管母细胞性脑膜瘤均发生于大脑，免疫组化Ｖｉｍ、ＥＭＡ、Ｋｅｒ阳性；３例脑膜的血管外皮瘤Ｖｉｍ阳性，而ＦⅧ与ＥＭＡ、Ｋｅｒ阴性。网状纤维染色显示瘤细胞围绕血管外周，网状纤维在血管外呈网状，组织病理改变和生物学特征也与软组织血管外皮瘤相似，提示其可能为来自脑脊膜的血管外皮细胞瘤。
23 cases of hemangioblastoma were observed by clinicopathological and immunohistochemical methods and compared with vascular hemangiomas and meningeal hemangiopericytoma. The results showed that 23 cases of hemangioblastoma occurred in cerebellum, endothelial cells F Ⅷ positive, stromal cells and Vim endothelial cells were positive; 5 cases of hemangioblastoma occurred in the brain, immunohistochemical Vim, EMA, Ker positive; 3 cases of meningeal vascular hemangiomas Vim positive, and FⅧ and EMA, Ker negative. The reticular fibers showed reticular formation outside the blood vessels. The pathological changes and biological characteristics of reticular fibers were also similar to those of soft tissue hemangiomas, suggesting that they may be hemangiopericytoma from the meninges.