甘氨酸亚铁对大鼠缺铁性贫血模型的影响

来源 :浙江中医药大学学报 | 被引量 : 0次 | 上传用户:JK0803_tangkai
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[目的]以Fe^2+作为中心金属离子,合成一种氨基酸配合物-甘氨酸亚铁(FeGly2),并对其补血作用进行研究。[方法]用甘氨酸和Fe^2+合成螯合铁,同时用红外光谱和原子吸收光谱对甘氨酸亚铁结构进行测定;并用大鼠贫血模型,观察甘氨酸亚铁补血作用。[结果]缺铁性贫血大鼠灌胃给予200mg/kg FeGly2和300mg/kg FeSO4制剂后,血液中血红蛋白(Hb)明显增加(P〈0.01),而且200mg/kg FeGly2和300mg/kg FeSO4制剂的升高血红蛋白含量的作用相当。[结论]甘氨酸亚铁
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