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目的探讨沙美特罗/替卡松混合干粉剂(舒利迭)吸入治疗儿童中、重度哮喘的临床疗效及其不良反应。方法本院2003年3月～2004年8月儿科门诊、急诊及住院的中、重度哮喘儿童120例,按单双日随机分组,治疗组选用舒利迭吸入,对照组吸入糖皮质激素(辅舒酮)治疗,分别对其临床疗效以及肺动能、不良反应进行观察研究。结果舒利迭吸入治疗组的临床疗效、肺功能改善方面明显优于辅舒酮对照组,具有统计学意义,未出现明显副作用。结论沙美特罗/替卡松联合治疗儿童中、重度哮喘,疗效明显优于单纯吸入糖皮质激素治疗,值得临床推广使用。
Objective To investigate the clinical effects and adverse reactions of salmeterol / ticasone mixed dry powder (seretide) inhalation in children with moderate and severe asthma. Methods 120 cases of pediatric outpatients, emergency department and hospitalized children with moderate or severe asthma in our hospital from March 2003 to August 2004 were randomly divided into single and double day. The patients in the treatment group were treated with inhaled glucocorticoid Shu ketone) treatment, respectively, its clinical efficacy and pulmonary motility, adverse reactions observed and studied. Results Seretide inhalation treatment group clinical efficacy, pulmonary function improved significantly better than the control group Fu-Shu ketone, with statistical significance, no significant side effects. Conclusions Salmeterol / Ticcatone combination treatment of children with moderate and severe asthma, the effect was significantly better than the simple inhalation of glucocorticoid therapy, worthy of clinical promotion and use.