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戊二醛是内窥镜检查时冷消毒最好的消毒剂,有很好的抗细菌和病毒活性,且损伤较小。戊二醛还用作冷却塔水中杀虫剂,电镜和 X 线片的固定液,皮革的揉革剂,以及用于多汗症的治疗。据报道接触戊二醛的量,即使在一般允许浓度以下也可致病。Norb(?)ck 调查了107名接触戊二醛的医务人员(戊组),其症状与对照组(未接触戊二醛)比较,发现戊组的鼻、咽部症状以及恶心、头痛、手部皮疹均明显高于对照组。有皮疹的人皮肤斑贴试验为阴性,说明戊二醛有直接刺激作用,而不是变态反应。一般症状随接触戊二醛量的增多而加重。所有人员的接触量均低于0.8mg/m~3。Jachuck 等考察了8名在窥镜室工作不足1个月的人员,其中2名已有症状,且观察到在允许量下,出现气道阻塞者1名,鼻炎和眼刺激症状者各6名,皮炎者3名。
Glutaraldehyde is the best disinfectant for cold disinfection in endoscopy and has good antibacterial and viral activity with less damage. Glutaraldehyde is also used as a fixative for pesticides, electron microscopes and X-rays in cooling tower water, as a kneading agent for leather, and for the treatment of hyperhidrosis. Exposure to glutaraldehyde is reported to be pathogenic even below the general allowable concentration. Norb (?) Ck investigated 107 glutaraldehyde-exposed medical staff (Group E) whose symptoms were compared with that of the control group (without exposure to glutaraldehyde) and found that the group had nasal and pharyngeal symptoms and nausea, headache, and hand Department of rash were significantly higher than the control group. Skin rash of people with skin patch test was negative, indicating that glutaraldehyde has a direct stimulating effect, rather than allergic reactions. General symptoms with the increase in the amount of glutaraldehyde and aggravate. The contact volume of all personnel is less than 0.8mg / m ~ 3. Jachuck et al examined eight people who worked less than one month in the endoscopy room, two of whom had symptoms and one who observed an airway obstruction with an allowable amount, six with rhinitis and ocular irritation , 3 dermatitis.