白细胞介素17(IL-17)在调节中性粒细胞补充和粒细胞生成方面扮演着非常重要的角色,而同时IL-17还是重要的促炎因子,可以诱导其他细胞因子和组织降解酶的产生,协同和提高一些细胞因子的功能,因此同时扮演防御和致病的角色。而牙周炎是最常见的口腔疾患之一,是由细菌引发的慢性炎症过程。现就IL-17的来源及家族、生物学特性以及在牙周炎的发病机制中起到的作用予以综述。 Interleukin 17 (IL-17) plays an important role in the regulation of neutrophil recruitment and granulocyte production, while IL-17 is also an important proinflammatory cytokine that induces other cytokines and tissue-degrading enzymes Produce, synergize, and enhance the function of some cytokines, thus playing both defensive and pathogenic roles. Periodontitis, one of the most common oral disorders, is a chronic inflammatory process triggered by bacteria. The origin and family, biological characteristics of IL-17 and its role in the pathogenesis of periodontitis are reviewed.