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温热疗法(Hyperthermia)近年来受到肿瘤临床的普遍重视。热疗中,如何设法有效地加热肿瘤患区,使之处于有效治疗高温范围(41～45℃),并尽可能不损伤周围正常组织,是能否取得较好疗效的关键。为此,首先要求热疗装置所产生热场分布的主要部分能覆盖住欲治疗区域。加热场在生物介质中的分布形态可由其比吸收率分布来描述。所谓比吸收率(specific absorption rate—SAR)是指单位质量生物组织所吸收的加热功率。比吸收率SAR分布表征热疗装置对生物组织的加热能力。根据有关热疗规范要求,热疗装置的50％SAR(相对于其最大值而言)分布应能覆盖住欲治疗区域。研究经验表明,若其80％等SAR线能包围肿瘤区,则基本上可达到既能有效杀死癌细胞,又不致损伤正常组织的理想热疗目标。
Hyperthermia has received widespread attention from clinical cancers in recent years. In hyperthermia, how to manage to effectively heat the affected area of the tumor to an effective therapeutic range (41-45°C), and to prevent damage to the surrounding normal tissue as much as possible, is the key to achieving better results. For this purpose, first of all, it is required that the main part of the thermal field generated by the hyperthermia device cover the area to be treated. The distribution pattern of the heating field in the biological medium can be described by its specific absorption rate distribution. The specific absorption rate (SAR) refers to the heating power absorbed by a unit mass of biological tissue. Specific Absorption Rate SAR Distribution Characterizes the heating capacity of a hyperthermia device to biological tissue. According to the requirements of the hyperthermia regulations, the 50% SAR (relative to its maximum value) distribution of the hyperthermia device should cover the area to be treated. Research experience shows that if 80% of SAR lines can surround the tumor area, it can basically achieve the ideal hyperthermia target that can effectively kill cancer cells without damaging normal tissues.