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目的探讨血清ɑ-L岩藻糖苷酶(AFU)和甲胎蛋白(AFP)的联合检测对原发性肝癌(PHC)诊断的临床意义。方法AFU采用酶法-CNPF测定法测定,以≥40U/L为阳性判断标准。AFP的含量采用电化学发光免疫分析测定。结果检测血清AFU在PHC中灵敏度较高,AFU和AFP联合检测,联合灵敏度为93.3%。结论联合检测AFU与AFP对提高PHC的诊断尤其是AFP阴性的PHC具有实用价值。
Objective To investigate the clinical significance of combined detection of serum fibrinolytic enzyme (AFU) and alpha-fetoprotein (AFP) in the diagnosis of primary hepatocellular carcinoma (PHC). Methods AFU enzyme-CNPF assay, to ≥ 40U / L as a positive criterion. The content of AFP was determined by electrochemiluminescence immunoassay. Results The detection of serum AFU was more sensitive in PHC. The combined detection of AFU and AFP had a combined sensitivity of 93.3%. Conclusions The combined detection of AFU and AFP has practical value in improving PHC diagnosis, especially AFP negative PHC.